Some players will go to parks that are favourable or unfavourable to them. Or leagues. And of course some players will be repeating or pushed agressively.
For fantasy purposes there is nothing better than knowing which players you expect to struggle and then be ready to jump on them when you get the chance. If you are any good in your league fellow team members will be very cautious if you show interest in a player. I prefer to get a list of players I expect to do very well and go after them agressively in the offseason. And those players that I expect to struggle I list and when I'm trading try to get that player added in.
Having said that, I haven't followed the minors as much this year. What players are going into difficult situations and you expect to struggle? And which have easy assignments and you expect to do well?