First Round
1. Pirates
2. Mariners
3. Diamondbacks
4. Orioles
5. Royals
6. Nationals
7. Diamondbacks (for failure to sign 2010 first-rounder Barret Loux)
8. Indians
9. Cubs
10. Padres (for failure to sign 2010 first-rounder Karsten Whitson)

11. Astros
12. Brewers
13. Mets
14. Marlins
15. Brewers (for failure to sign 2010 first-rounder Dylan Covey)
16. Dodgers
17. Angels
18. Athletics
19. Red Sox (from Tigers for Victor Martinez, Type A)
20. Rockies
21. Blue Jays
22. Cardinals
23. Nationals (from White Sox for Adam Dunn, Type A)
24. Rays (from Red Sox for Carl Crawford, Type A)
25. Padres
26. Red Sox (from Rangers for Adrian Beltre, Type A)
27. Reds
28. Braves
29. Giants
30. Twins
31. Rays (from Yankees for Rafael Soriano, Type A)
32. Rays
33. Rangers (from Phillies for Cliff Lee, Type A)
Supplemental First Round
34. Nationals (Dunn)
35. Blue Jays (for Scott Downs, Type A, to Angels)
36. Red Sox (Martinez)
37. Rangers (Lee)
38. Rays (Crawford)
39. Phillies (for Jayson Werth, Type A, to Nationals)
40. Red Sox (Beltre)
41. Rays (Soriano)
42. Rays (for Grant Balfour, Type A, to Athletics)
43. Diamondbacks (for Adam LaRoche, Type B, to Nationals)
44. Mets (for Pedro Feliciano, Type B, to Yankees)
45. Rockies (for Octavio Dotel, Type B, to Blue Jays)
46. Blue Jays (for John Buck, Type B, to Marlins)
47. White Sox (for J.J. Putz, Type B, to Diamondbacks)
47a. Red Sox (if Felipe Lopez, Type B, signs a big league deal elsewhere)
48. Padres (for Jon Garland, Type B, to Dodgers)
49. Giants (for Juan Uribe, Type B, to Dodgers)
50. Twins (for Orlando Hudson, Type B, to Padres)
51. Yankees (for Javier Vazquez, Type B, to Marlins)
52. Rays (for Joaquin Benoit, Type B, to Tigers)
53. Blue Jays (for Miguel Olivo, Type B, to Mariners)
54. Padres (for Yorvit Torrealba, Type B, to Rangers)
55. Twins (for Jesse Crain, Type B, to White Sox)
56. Rays (for Randy Choate, Type B, to Marlins)
57. Blue Jays (for Kevin Gregg, Type B, to Orioles)
58. Padres (for Kevin Correia, Type B, to Pirates)
59. Rays (for Brad Hawpe, Type B, to Padres)
60. Rays (for Chad Qualls, Type B, to Padres)
Second-Round Changes
66. Phillies (from Nationals for Werth)
74. Blue Jays (from Angels for Downs)
75. Rays (from Athletics for Balfour)
Third-Round Changes
None
Supplemental Third Round
121. Mariners (for failure to sign 2010 third-rounder Ryne Stanek)